What in my sample buffer could hinder my ability to achieve good mass spectrometry data?

Detergents usually show up as a bell shaped curve with each peak having the same mass difference from each other. Detergent peaks are usually so abundant that they overhsadow any peptide . Some detergent we can get rid of, some we cannot. Please contact us if you have any detergent in your sample.

Other things to watch out for

  • Glycerol
  • large amounts of Urea (> 6M)

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Category: Sample Preparation

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